Singles or pairs in cancer cells

Two human embryonic kidney cells expressing CXCR4 receptor (in dark yellow). CREDIT © Paolo Annibale, Ali Isbilir, MDC It all sounds similar to a dance event - but are singles or couples dancing here? This was the question Ali Isbilir and Dr. Paolo Annibale at the Max Delbrück Center for Molecular Medicine in the Helmholtz … Continue reading Singles or pairs in cancer cells

Breaking bad: how shattered chromosomes make cancer cells drug-resistant

Researchers find that the phenomenon of chromothripsis results in rearranged genomes and extra-chromosomal DNA that helps mutated cells not only evade treatment, but become more aggressive. Scanning electron micrograph of the nucleus of a cancer cell, chromosomes are indicated by blue arrows and circular extra-chromosomal DNA are indicated by orange arrows. CREDIT Paul Mischel, UC … Continue reading Breaking bad: how shattered chromosomes make cancer cells drug-resistant

New treatment could spare early-stage rectal cancer patients life-altering side effects

The equipment for transanal endoscopic microsurgery is geared towards small and precise operations, and includes a camera, electrical knife, grasping forceps and suction device. CREDIT: STAR TREC clinical trial. A new and less invasive treatment developed by Cancer Research UK researchers is safer than standard major surgery for early-stage rectal cancer, giving patients a better … Continue reading New treatment could spare early-stage rectal cancer patients life-altering side effects

Predicting the risk of severe side effects during cancer therapy

The risk of serious adverse effects on the blood status and bone marrow of patients during chemotherapy can be predicted by a model developed at Linköping University, Sweden. This research may make it possible to use genetic analysis to identify patients with a high probability of side effects.  Photo by Marcelo Leal on Unsplash It … Continue reading Predicting the risk of severe side effects during cancer therapy

Risk of heart disease in breast cancer patients can be predicted from routine scans

Women who have been treated for breast cancer may have a higher risk of developing cardiovascular disease and in some groups the risk of dying from cardiovascular disease is higher than the risk of dying from breast cancer. The new study shows that it is possible to spot those at the greatest risk using computer analysis … Continue reading Risk of heart disease in breast cancer patients can be predicted from routine scans

Coffee consumption and survival in patients with colorectal cancer

Is increased coffee consumption associated with improved survival in patients with advanced or metastatic colorectal cancer? In a study of 1171 patients with advanced or metastatic colorectal cancer, increased coffee consumption was associated with a lower risk of disease progression and death. Significant associations were noted for both caffeinated and decaffeinated coffee.Among patients with advanced … Continue reading Coffee consumption and survival in patients with colorectal cancer

Scientists accelerate progress in preventing drug resistance in lung and pancreas cancers

Scientists at the Huntsman Cancer Institute (HCI) at the University of Utah (U of U) report today the development of new models to study molecular characteristics of tumors of the lung and pancreas that are driven by mutations in a gene named NTRK1. In healthy bodies, NTRK1 has critical functions in the development of nerve cells, … Continue reading Scientists accelerate progress in preventing drug resistance in lung and pancreas cancers

Breast cancer deadlier in heart attack survivors

Breast Cancer patients are 60 percent more likely to die of cancer after surviving a heart attack, a new study finds. Led by researchers at NYU Grossman School of Medicine, the study shows how heart attacks, by blocking blood flow through arteries, trigger a specific, pro-cancer immune reaction. Designed by evolution to attack invading bacteria … Continue reading Breast cancer deadlier in heart attack survivors

Study shows opioid, sedative and antidepressant use pre-surgery leads to worse outcomes

Patients who already used opioids, sedatives or antidepressants prior to colorectal surgery may experience significantly more complications post-surgery.  The study examined 1,201 patients 18 years of age and older who underwent colorectal resection for any indication other than trauma at UK HealthCare. Of these patients, roughly 30% used opioids, 28% used antidepressants and 18% used sedatives, … Continue reading Study shows opioid, sedative and antidepressant use pre-surgery leads to worse outcomes

Are older adults getting the most effective cancer treatments?

As people age, cancer becomes an increasing health concern. Solid cancer tumors are cancers that don't affect the blood and instead form tumors, or growths of abnormal cells in certain parts of the body. These solid cancer tumors mainly impact people who are 65 and older. If you or an older loved one is diagnosed with … Continue reading Are older adults getting the most effective cancer treatments?