Long-term follow-up shows need for new chemotherapy strategies for rectal cancer

Results of EORTC trial 22921 at 10.4 years median follow-up Appearing in Lancet Oncology, long term results of EORTC trial 22921 with 10.4 years median follow-up show that 5-FU (fluorouracil) based adjuvant chemotherapy after preoperative (chemo)-radiotherapy for patients with cT3-resectable T4 M0 rectal cancer does not improve survival or disease-free survival. EORTC trial 22921 explored the … Continue reading Long-term follow-up shows need for new chemotherapy strategies for rectal cancer

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Breast cancer in young women after treatment for Hodgkin’s disease

Girls treated for Hodgkin's disease during adolescence acquire a considerable risk of developing breast cancer, as shown by an observational study published in the current issue of Deutsches Ärzteblatt International. The study, which was carried out by Günther Schellong and his colleagues in the German Working Group on the Long-Term Sequelae of Hodgkin's Disease, has an … Continue reading Breast cancer in young women after treatment for Hodgkin’s disease

Physical activity seems to significantly extend lives of cancer survivors

Reduces mortality by up to 48 percent according to study Physical activity significantly extends the lives of male cancer survivors, a new study of 1,021 men has found. During the period while the men were followed, those who expended more than 12,600 calories per week in physical activity were 48 percent less likely to die than … Continue reading Physical activity seems to significantly extend lives of cancer survivors

Breakthrough announced in treatment of patient with rare type of leukemia

University of Leicester researchers deploy 'precision medicine' to successfully target advanced form of leukaemia with skin cancer drug A team of scientists from the University of Leicester has demonstrated a novel treatment for Hairy Cell Leukaemia (HCL), a rare type of blood cancer, using a drug administered to combat skin cancer. The research, which is published … Continue reading Breakthrough announced in treatment of patient with rare type of leukemia

New analysis shows fewer years of life lost to cancer

Since the enactment of the National Cancer Act in 1971, the U.S. has spent hundreds of billions of dollars in cancer research and treatment. And yet, the cancer mortality rate - the historic benchmark of progress - has only declined modestly while the mortality rates of other leading causes of death have declined substantially. This … Continue reading New analysis shows fewer years of life lost to cancer

Most women undergoing surgery for vulvar cancer maintain healthy body image and sex life

A new study finds that most women who undergo conservative surgery for vulvar cancer experience little to no long-term disruption to sexuality and body image. Published early online in the Journal of Advanced Nursing, the study also reveals factors that can increase women's risk of feeling negative emotions after surgery. Women diagnosed with vulvar cancer are … Continue reading Most women undergoing surgery for vulvar cancer maintain healthy body image and sex life

Antipsychotic drug exhibits cancer-fighting properties

In zebrafish model, perphenazine activates therapeutic pathway for intractable leukemia, may hold promise for other tumor In a prime example of finding new uses for older drugs, studies in zebrafish show that a 50-year-old antipsychotic medication called perphenazine can actively combat the cells of a difficult-to-treat form of acute lymphoblastic leukemia (ALL). The drug works … Continue reading Antipsychotic drug exhibits cancer-fighting properties

New study shows promise for preventing therapy resistance in tumor cells

A new study led by University of Kentucky researchers suggests that activating the tumor suppressor p53 in normal cells causes them to secrete Par-4, another potent tumor suppressor protein that induces cell death in cancer cells. This finding may help researchers decipher how to inhibit the growth of tumors that have become resistant to other … Continue reading New study shows promise for preventing therapy resistance in tumor cells