Study finds how diabetes drug metformin inhibits progression of pancreatic cancer

Metformin-induced suppression of metastasis-promoting tumor microenvironment may be most prevalent in overweight, obese patients Massachusetts General Hospital (MGH) investigators may have uncovered a novel mechanism behind the ability of the diabetes drug metformin to inhibit the progression of pancreatic cancer. In their report that has been published in the open access journal PLOS One, the … Continue reading Study finds how diabetes drug metformin inhibits progression of pancreatic cancer

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Palliative care initiated in the emergency department is associated with improved quality of life

A palliative care consultation initiated in the emergency department (ED) for patients with advanced cancer was associated with improved quality of life and did not seem to shorten survival, according to an article published online by JAMA Oncology. ​ Visits to the ED are common for patients with advanced cancer and it is during these visits … Continue reading Palliative care initiated in the emergency department is associated with improved quality of life

Racial disparity lies at the intersection of HIV and Hodgkin lymphoma

A new study finds a significant racial disparity within a doubly troubled population of patients: those with HIV and Hodgkin lymphoma. In such cases, blacks are at significantly higher risk than whites of not receiving treatment for the cancer that in many cases would be effective. "Black patients have higher rates of not receiving treatment," … Continue reading Racial disparity lies at the intersection of HIV and Hodgkin lymphoma

Mapping cancer’s ‘social networks’ opens new approaches to treatment

Cancer Research UK-funded scientists have designed a computer model that applies techniques used to analyse social networks to identify new ways of treating cancer, according to research published in PLOS Computational Biology. The model analyses the unique behaviours of cancer-causing proteins - spotting what makes them different from normal proteins, and mapping out molecular targets for new … Continue reading Mapping cancer’s ‘social networks’ opens new approaches to treatment

Financial burden of cancer survivorship varies by age

Survivors of cancer pay thousands of dollars in excess medical expenditures every year, with the excess financial burden varying by age and cancer site, according to a new American Cancer Society study. The study, appearing early online in the Journal of the National Cancer Institute, says targeted efforts will be important to reduce the economic burden … Continue reading Financial burden of cancer survivorship varies by age