Ibrutinib linked to high blood pressure and other heart problems

Hypertension with ibrutinib more common than previously reported; this study is first to show an association between cancer drug-related hypertension and other heart problems. Over half of the people prescribed the targeted blood cancer-fighting drug ibrutinib developed new or worsened high blood pressure within six months of starting the medication, according to a new study … Continue reading Ibrutinib linked to high blood pressure and other heart problems

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Cancer survivors likely to face increase in long-term risk of cardiovascular disease

New estimates suggest strategies to reduce the risk of cardiovascular disease are needed for the growing population of cancer survivors. In one of the largest studies of its kind, the research team, led by the London School of Hygiene & Tropical Medicine, analysed the medical records of more than 630,000 people in the UK, including over … Continue reading Cancer survivors likely to face increase in long-term risk of cardiovascular disease

Many of the deadliest cancers receive the least amount of research funding

'Embarrassing' or stigmatized cancers like lung and liver are underfunded Poorly funded cancers: colon, endometrial, liver and bile duct, cervical, ovarian, pancreatic and lung Well-funded cancers: breast, pediatric, leukemia and lymphoma All cancers with stigmatized behavior (i.e. lung cancer and smoking) are poorly funded Underfunding of these common cancers could negatively impact research, drug development … Continue reading Many of the deadliest cancers receive the least amount of research funding

Biomaterial-delivered chemotherapy leads to long-term survival in brain cancer

A combination of chemotherapy drugs during brain cancer surgery using a biodegradable paste, leads to long-term survival, researchers at the University of Nottingham have discovered. In a new study published in Clinical Cancer Research, scientists found a significant survival benefit in rat models with brain tumours when a combination of two chemotherapy drugs, (etoposide and temozolomide), … Continue reading Biomaterial-delivered chemotherapy leads to long-term survival in brain cancer

Timed release of turmeric stops cancer cell growth

A Washington State University research team has developed a drug delivery system using curcumin, the main ingredient in the spice turmeric, that successfully inhibits bone cancer cells while promoting growth of healthy bone cells. The work could lead to better post-operative treatments for people with osteosarcoma, the second most prevalent cause of cancer death in … Continue reading Timed release of turmeric stops cancer cell growth

Recovering reproduction in girls who survive childhood cancer

Leukemia treatments often leave girls infertile, but a procedure developed by researchers at the University of Michigan working with mice is a step toward restoring their ability to be biological mothers. ​ Ovarian follicles are the "nests" that carry eggs and support them to grow and become viable. The researchers demonstrated that they could dramatically … Continue reading Recovering reproduction in girls who survive childhood cancer

New study underscores significant benefit of conversations between clinicians and patients

Across the United States, millions of individuals face serious, life-limiting illness like cancer, heart disease and stroke, respiratory disease and diabetes. The final year of life with serious illness can be filled with emotional distress and uncertainty about treatment options.   When people with serious illness have conversations with their doctors and nurses about their … Continue reading New study underscores significant benefit of conversations between clinicians and patients

Stress hormones promote breast cancer metastasis

It has long been thought that stress contributes to cancer progression. Scientists from the University of Basel and the University Hospital of Basel have deciphered the molecular mechanisms linking breast cancer metastasis with increased stress hormones. In addition, they found that synthetic derivatives of stress hormones, which are frequently used as anti-inflammatory in cancer therapy, … Continue reading Stress hormones promote breast cancer metastasis

Greater efforts needed to address cancer therapies’ effects on bone health

 A new British Journal of Clinical Pharmacology review examines the impact of cancer therapies on the skeleton and how to limit bone loss and fractures in cancer patients treated with these therapies. The review notes that efforts to limit the effects of cancer therapies on bone have nearly universally employed anti-resorptive agents that reduce bone turnover, and … Continue reading Greater efforts needed to address cancer therapies’ effects on bone health

Discovery may bolster chemotherapy potency while protecting the heart from side-effects

Researchers from the University of Alberta may have found a way to make chemotherapy more effective at treating cancer while blocking its harmful side-effects on the heart. While chemotherapy can be an effective treatment for cancer, the aggressive attack on cancer cells often cause damage to other cells throughout the body, including the heart, making … Continue reading Discovery may bolster chemotherapy potency while protecting the heart from side-effects