Biomaterial-delivered chemotherapy leads to long-term survival in brain cancer

A combination of chemotherapy drugs during brain cancer surgery using a biodegradable paste, leads to long-term survival, researchers at the University of Nottingham have discovered. In a new study published in Clinical Cancer Research, scientists found a significant survival benefit in rat models with brain tumours when a combination of two chemotherapy drugs, (etoposide and temozolomide), … Continue reading Biomaterial-delivered chemotherapy leads to long-term survival in brain cancer

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Timed release of turmeric stops cancer cell growth

A Washington State University research team has developed a drug delivery system using curcumin, the main ingredient in the spice turmeric, that successfully inhibits bone cancer cells while promoting growth of healthy bone cells. The work could lead to better post-operative treatments for people with osteosarcoma, the second most prevalent cause of cancer death in … Continue reading Timed release of turmeric stops cancer cell growth

Recovering reproduction in girls who survive childhood cancer

Leukemia treatments often leave girls infertile, but a procedure developed by researchers at the University of Michigan working with mice is a step toward restoring their ability to be biological mothers. ​ Ovarian follicles are the "nests" that carry eggs and support them to grow and become viable. The researchers demonstrated that they could dramatically … Continue reading Recovering reproduction in girls who survive childhood cancer

New study underscores significant benefit of conversations between clinicians and patients

Across the United States, millions of individuals face serious, life-limiting illness like cancer, heart disease and stroke, respiratory disease and diabetes. The final year of life with serious illness can be filled with emotional distress and uncertainty about treatment options.   When people with serious illness have conversations with their doctors and nurses about their … Continue reading New study underscores significant benefit of conversations between clinicians and patients

Stress hormones promote breast cancer metastasis

It has long been thought that stress contributes to cancer progression. Scientists from the University of Basel and the University Hospital of Basel have deciphered the molecular mechanisms linking breast cancer metastasis with increased stress hormones. In addition, they found that synthetic derivatives of stress hormones, which are frequently used as anti-inflammatory in cancer therapy, … Continue reading Stress hormones promote breast cancer metastasis

Greater efforts needed to address cancer therapies’ effects on bone health

 A new British Journal of Clinical Pharmacology review examines the impact of cancer therapies on the skeleton and how to limit bone loss and fractures in cancer patients treated with these therapies. The review notes that efforts to limit the effects of cancer therapies on bone have nearly universally employed anti-resorptive agents that reduce bone turnover, and … Continue reading Greater efforts needed to address cancer therapies’ effects on bone health

Discovery may bolster chemotherapy potency while protecting the heart from side-effects

Researchers from the University of Alberta may have found a way to make chemotherapy more effective at treating cancer while blocking its harmful side-effects on the heart. While chemotherapy can be an effective treatment for cancer, the aggressive attack on cancer cells often cause damage to other cells throughout the body, including the heart, making … Continue reading Discovery may bolster chemotherapy potency while protecting the heart from side-effects

Increased risk of heart attack and stroke in older adults leading up to a cancer diagnosis

Older adults with cancer are more likely to have had a heart attack or stroke in the months prior to their cancer diagnosis compared with similar adults who do not have cancer during the same period, according to a report published online in Blood. Lung and colon cancers, as well as advanced-staged cancers, appear to be most strongly … Continue reading Increased risk of heart attack and stroke in older adults leading up to a cancer diagnosis

Opioid use and misuse following treatment for head and neck cancer

Cancer patients are often prescribed pain medications, for example during recovery from surgical procedures. However, for many cancer patients, the use of opioid pain medications during treatment can be a gateway to misuse or addiction once treatment ends. Now with cancer patients living longer than ever before, protecting quality of life in the months, years, … Continue reading Opioid use and misuse following treatment for head and neck cancer

Genome offers clues to esophageal cancer disparity which could be prevented by flavonoids derived from cranberries

A genomic duplication may help explain why esophageal adenocarcinoma is much more common in Caucasians and presents a potential target for prevention. A change in the genome of Caucasians could explain much-higher rates of the most common type of esophageal cancer in this population, a new study finds. It suggests a possible target for prevention strategies, … Continue reading Genome offers clues to esophageal cancer disparity which could be prevented by flavonoids derived from cranberries