Proton therapy lowers risk of side effects in cancer compared to traditional radiation

Proton therapy leads to significantly lower risk of side effects severe enough to lead to unplanned hospitalizations for cancer patients when compared with traditional radiation, while cure rates between the two groups are almost identical. The findings come from an expanded analysis of the largest review of its kind, performed by researchers in the Perelman … Continue reading Proton therapy lowers risk of side effects in cancer compared to traditional radiation

Scientists show thin metal mesh loaded with T cells shrinks solid tumors

What if a metal that's already used to repair broken bones, straighten teeth and keep arteries from clogging could also be used to stop your cancer from spreading? New findings published in Nature Biomedical Engineering from scientists at Fred Hutchinson Cancer Research Center show for the first time that a piece of small, thin metal mesh loaded with cancer-fighting … Continue reading Scientists show thin metal mesh loaded with T cells shrinks solid tumors

Pacemakers can improve heart function in patients with chemotherapy-induced heart disease

With the advent of new therapies, cancer patients are surviving longer than ever before -- but the incidence of side-effect chemotherapy-induced cardiomyopathy (CHIC), or weakness of the heart muscle, is increasing. Research published in JAMA has shown that treating CHIC with commercially available cardiac resynchronization therapy (CRT) delivered through a surgically implanted defibrillator or pacemaker can significantly … Continue reading Pacemakers can improve heart function in patients with chemotherapy-induced heart disease

Ibrutinib linked to high blood pressure and other heart problems

Hypertension with ibrutinib more common than previously reported; this study is first to show an association between cancer drug-related hypertension and other heart problems. Over half of the people prescribed the targeted blood cancer-fighting drug ibrutinib developed new or worsened high blood pressure within six months of starting the medication, according to a new study … Continue reading Ibrutinib linked to high blood pressure and other heart problems

Cancer survivors likely to face increase in long-term risk of cardiovascular disease

New estimates suggest strategies to reduce the risk of cardiovascular disease are needed for the growing population of cancer survivors. In one of the largest studies of its kind, the research team, led by the London School of Hygiene & Tropical Medicine, analysed the medical records of more than 630,000 people in the UK, including over … Continue reading Cancer survivors likely to face increase in long-term risk of cardiovascular disease

Many of the deadliest cancers receive the least amount of research funding

'Embarrassing' or stigmatized cancers like lung and liver are underfunded Poorly funded cancers: colon, endometrial, liver and bile duct, cervical, ovarian, pancreatic and lung Well-funded cancers: breast, pediatric, leukemia and lymphoma All cancers with stigmatized behavior (i.e. lung cancer and smoking) are poorly funded Underfunding of these common cancers could negatively impact research, drug development … Continue reading Many of the deadliest cancers receive the least amount of research funding

Biomaterial-delivered chemotherapy leads to long-term survival in brain cancer

A combination of chemotherapy drugs during brain cancer surgery using a biodegradable paste, leads to long-term survival, researchers at the University of Nottingham have discovered. In a new study published in Clinical Cancer Research, scientists found a significant survival benefit in rat models with brain tumours when a combination of two chemotherapy drugs, (etoposide and temozolomide), … Continue reading Biomaterial-delivered chemotherapy leads to long-term survival in brain cancer

Timed release of turmeric stops cancer cell growth

A Washington State University research team has developed a drug delivery system using curcumin, the main ingredient in the spice turmeric, that successfully inhibits bone cancer cells while promoting growth of healthy bone cells. The work could lead to better post-operative treatments for people with osteosarcoma, the second most prevalent cause of cancer death in … Continue reading Timed release of turmeric stops cancer cell growth

Recovering reproduction in girls who survive childhood cancer

Leukemia treatments often leave girls infertile, but a procedure developed by researchers at the University of Michigan working with mice is a step toward restoring their ability to be biological mothers. ​ Ovarian follicles are the "nests" that carry eggs and support them to grow and become viable. The researchers demonstrated that they could dramatically … Continue reading Recovering reproduction in girls who survive childhood cancer

New study underscores significant benefit of conversations between clinicians and patients

Across the United States, millions of individuals face serious, life-limiting illness like cancer, heart disease and stroke, respiratory disease and diabetes. The final year of life with serious illness can be filled with emotional distress and uncertainty about treatment options.   When people with serious illness have conversations with their doctors and nurses about their … Continue reading New study underscores significant benefit of conversations between clinicians and patients