High doses of vitamin C to improve cancer treatment passes human safety trial

Clinical trials found that it is safe to regularly infuse brain and lung cancer patients with 800-1000 times the daily recommended amount of vitamin C as a potential strategy to improve outcomes of standard cancer treatments. In a work presented March 30, 2017 in Cancer Cell, University of Iowa researchers also show pathways by which altered … Continue reading High doses of vitamin C to improve cancer treatment passes human safety trial

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Treatment significantly reduces chemotherapy-induced hearing loss in children

Investigators from Children's Hospital Los Angeles and 37 other Children's Oncology Group hospitals in the U.S. and Canada have determined that sodium thiosulfate prevents cisplatin-induced hearing loss in children and adolescents with cancer. Results of this randomized, controlled, phase 3 study, called ACCL0431, have been published in the early online edition of Lancet Oncology. "This federally-funded, … Continue reading Treatment significantly reduces chemotherapy-induced hearing loss in children

Chemotherapy and exercise: The right dose of workout helps side effects

Researchers at the University of Rochester Wilmot Cancer Institute discovered something simple and inexpensive to reduce neuropathy in hands and feet due to chemotherapy - exercise. The study, involving more than 300 cancer patients, is to be presented this weekend and honored as a "Best of ASCO" among 5,800 abstracts at the world's largest gathering … Continue reading Chemotherapy and exercise: The right dose of workout helps side effects

Eye movement affected in former childhood cancer patients

Nowadays, the lives of the majority of all children with cancer can be spared. However, the cure for the disease comes with a price: some of the survivors will suffer long-term injury from the treatment. A study from Lund University in Sweden now shows that commonly used chemo toxins impair the eyesight in childhood cancer … Continue reading Eye movement affected in former childhood cancer patients

Chemoradiation may increase survival for a subset of elderly head and neck cancer patients

The addition of chemotherapy (CT) to radiation therapy (RT) improves survival rates among a subset of elderly head and neck cancer patients, specifically those ages 71 to 79 with low comorbidity scores and advanced disease stage, according to University of Colorado Cancer Center research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium. While … Continue reading Chemoradiation may increase survival for a subset of elderly head and neck cancer patients

Racial disparity lies at the intersection of HIV and Hodgkin lymphoma

A new study finds a significant racial disparity within a doubly troubled population of patients: those with HIV and Hodgkin lymphoma. In such cases, blacks are at significantly higher risk than whites of not receiving treatment for the cancer that in many cases would be effective. "Black patients have higher rates of not receiving treatment," … Continue reading Racial disparity lies at the intersection of HIV and Hodgkin lymphoma

New smart robot accelerates cancer treatment research

A new smart research robot accelerates research on cancer treatments by finding optimal treatment combinations.  Complex diseases like cancer are almost exclusively treated by combining several different drugs. These combinations are typically composed from drugs that show an effect on their own, but do not necessarily constitute the best possible combinations. The new robot system … Continue reading New smart robot accelerates cancer treatment research

Combining chemotherapy with an immune-blocking drug could stop cancer growing back

Giving patients a drug that blocks part of the immune system from going into overdrive might help prevent cancer coming back in some people, according to research published today in Cancer Research. Cancer Research UK-funded scientists from the University of Sheffield found that the cancer-killing action of chemotherapy can trigger a swarm of wound-healing, white blood … Continue reading Combining chemotherapy with an immune-blocking drug could stop cancer growing back

One-two punch catches cancer cells in vulnerable state

Timing may be decisive when it comes to overcoming cancer's ability to evade treatment. By hitting breast cancer cells with a targeted therapeutic immediately after chemotherapy, researchers from Brigham and Women's Hospital (BWH) were able to target cancer cells during a transitional stage when they were most vulnerable, killing cells and shrinking tumors in the … Continue reading One-two punch catches cancer cells in vulnerable state

Risk for leukemia after treatment for early-stage breast cancer higher than reported

The risk of developing leukemia after radiation therapy or chemotherapy for early stage breast cancer remains very small, but it is twice as high as previously reported, according to results of a new study led by researchers at the Johns Hopkins Kimmel Cancer Center. The study team reviewed data on 20,063 breast cancer patients treated … Continue reading Risk for leukemia after treatment for early-stage breast cancer higher than reported