Aspirin could hold the key to supercharged cancer immunotherapy

Giving cancer patients aspirin at the same time as immunotherapy could dramatically boost the effectiveness of the treatment, according to new research published in the journal┬áCell. Francis Crick Institute researchers, funded by Cancer Research UK, have shown that skin, breast and bowel cancer cells often produce large amounts of prostaglandin E2 (PGE2). This molecule dampens … Continue reading Aspirin could hold the key to supercharged cancer immunotherapy

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Key factor discovered in the formation of metastases in melanoma

Patients who visit the doctor because of malignant skin cancer often go too late - the aggressive cancer has already formed numerous metastases in their bodies. This rapid, malignant metastatic formation of melanoma, was previously put down to the high mutation rate that is characteristic of melanoma, i.e. genetic changes that stimulate the growth of … Continue reading Key factor discovered in the formation of metastases in melanoma

Researchers map paths to cancer drug resistance

A team of researchers have identified key events that prompt certain cancer cells to develop resistance to otherwise lethal therapies.By mapping the specific steps that cells of melanoma, breast cancer and a blood cancer called myelofibrosis use to become resistant to drugs, the researchers now have much better targets for blocking those pathways and keeping … Continue reading Researchers map paths to cancer drug resistance