Cholesterol byproduct hijacks immune cells to spread breast cancer

High cholesterol levels have been associated with breast cancer spreading to other sites in the body, but doctors and researchers don't know the cause for the link. A new study by University of Illinois researchers found that the culprit is a byproduct of cholesterol metabolism that acts on specific immune cells so that they facilitate … Continue reading Cholesterol byproduct hijacks immune cells to spread breast cancer

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Decreased blood vessel leakage can improve cancer therapy and reduce tumor spread

Cancer therapy is often hampered by the accumulation of fluids in and around the tumour, which is caused by leakage from the blood vessels in the tumour. Researchers at Uppsala University now show how leakage from blood vessels is regulated. They have identified a novel mechanism whereby leakage can be suppressed to improve the result … Continue reading Decreased blood vessel leakage can improve cancer therapy and reduce tumor spread

Pancreas cancer spreads from multiple types of wayward cells

Penn animal study has implications for better drug design, 'unprecedented window' into tumor evolution. Tumor cells associated with pancreatic cancer often behave like communities by working with each other to increase tumor spread and growth to different organs. Groups of these cancer cells are better than single cancer cells in driving tumor spread, according to … Continue reading Pancreas cancer spreads from multiple types of wayward cells

Cancer survivors have evolving information needs

Cancer patient's information needs appear to differ depending on the type of cancer they have and where they are in their survivorship. Clinicians caring for cancer survivors may need to understand these needs in order to better address survivor's concerns about cancer recurrence, late effects, and family member's risks. A three-year study of over 2,000 … Continue reading Cancer survivors have evolving information needs

Key factor discovered in the formation of metastases in melanoma

Patients who visit the doctor because of malignant skin cancer often go too late - the aggressive cancer has already formed numerous metastases in their bodies. This rapid, malignant metastatic formation of melanoma, was previously put down to the high mutation rate that is characteristic of melanoma, i.e. genetic changes that stimulate the growth of … Continue reading Key factor discovered in the formation of metastases in melanoma

Osteoporosis treatment may also benefit breast cancer patients

Treatment approaches to reduce the risk of bone complications (metastasis) associated with breast cancer may be one step closer to becoming a reality.  According to a study led by a team at the Research Institute of the McGill University Health Centre (RI-MUHC), findings show that medication used to treat bone deterioration in post-menopausal women may … Continue reading Osteoporosis treatment may also benefit breast cancer patients

Novel immunotherapy vaccine decreases recurrence in HER2 positive breast cancer patients

Women who received trastuzumab, Herceptin, as part of standard treatment show greatest benefit A new breast cancer vaccine candidate, (GP2), provides further evidence of the potential of immunotherapy in preventing disease recurrence. This is especially the case for high-risk patients when it is combined with a powerful immunotherapy drug. These findings are being presented by … Continue reading Novel immunotherapy vaccine decreases recurrence in HER2 positive breast cancer patients

Aspirin may slow recurrence in breast cancer patients

New findings published today in the journal Cancer Research reveal that some postmenopausal overweight breast cancer patients who use common anti-inflammatory drugs like aspirin or ibuprofen have significantly lower breast cancer recurrence rates. Researchers from the Cancer Therapy & Research Center at The University of Texas Health Science Center at San Antonio and the University of Texas … Continue reading Aspirin may slow recurrence in breast cancer patients

Dormant prostate cancer cells may be reawakened by factors produced in inflammatory cells

Researchers in the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute discovered in pre-clinical models that dormant prostate cancer cells found in bone tissue can be reawakened, causing metastasis to other parts of the body. Understanding this mechanism of action may allow researchers to intervene prior to disease progression. "Understanding how and why dormant cells in bone … Continue reading Dormant prostate cancer cells may be reawakened by factors produced in inflammatory cells

Technique filters cancer where chemo can’t reach

A cancer therapy that removes malignant cells from a patient's cerebrospinal fluid may soon be available to prevent metastases and decrease complications of cancers involving the brain, according to Penn State medical researchers. Many cancer types metastasize to the brain -- including breast cancer, pancreatic cancer, prostate cancer and leukemia -- but by filtering these malignant … Continue reading Technique filters cancer where chemo can’t reach