Scientists link pancreatic cancer survival to four genes

Alterations in four main genes are responsible for how long patients survive with pancreatic cancer, according to a new study in JAMA Oncology. Before now, the presence and patterns between the genes and disease progression was not clearly established. One key difference in this study is the relatively large size: it involved 356 patients who all had … Continue reading Scientists link pancreatic cancer survival to four genes

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Natural compound from a deep-water marine sponge found to reduce pancreatic tumor size

Scientists at Florida Atlantic University's Harbor Branch Oceanographic Institute found that a deep-water marine sponge collected off of Fort Lauderdale's coast contains leiodermatolide, a natural product that has the ability to inhibit the growth of cancer cells as well as block cancer cells from dividing using extremely low concentrations of the compound. This work resulted … Continue reading Natural compound from a deep-water marine sponge found to reduce pancreatic tumor size

Study finds how diabetes drug metformin inhibits progression of pancreatic cancer

Metformin-induced suppression of metastasis-promoting tumor microenvironment may be most prevalent in overweight, obese patients Massachusetts General Hospital (MGH) investigators may have uncovered a novel mechanism behind the ability of the diabetes drug metformin to inhibit the progression of pancreatic cancer. In their report that has been published in the open access journal PLOS One, the … Continue reading Study finds how diabetes drug metformin inhibits progression of pancreatic cancer

Pancreas cancer spreads from multiple types of wayward cells

Penn animal study has implications for better drug design, 'unprecedented window' into tumor evolution. Tumor cells associated with pancreatic cancer often behave like communities by working with each other to increase tumor spread and growth to different organs. Groups of these cancer cells are better than single cancer cells in driving tumor spread, according to … Continue reading Pancreas cancer spreads from multiple types of wayward cells

Wild berry extract may strengthen effectiveness of pancreatic cancer drug

Worth considering micronutrient and drug combo for hard to treat cancers, say researchers The findings prompt the researchers to suggest that adding 'nutraceuticals' to chemotherapy cycles may improve the effectiveness of conventional drugs, particularly in hard to treat cancers, such as pancreatic cancer. They base their findings on the effectiveness of extract of chokeberry (Aronia melanocarpa) … Continue reading Wild berry extract may strengthen effectiveness of pancreatic cancer drug

Pancreatic survival rates at standstill for 4 decades

Long-term survival from pancreatic cancer has failed to improve in 40 years – with the outlook remaining the lowest of the 21 most common cancers, according to new figures published by Cancer Research UK. Today just over three per cent of pancreatic cancer patients survive for at least five years, only a fraction more than the … Continue reading Pancreatic survival rates at standstill for 4 decades

Unique study focuses on combined treatment approach for locally advanced pancreatic cancer

The study and accompanying clinical trial aim to identify tumor biomarkers and provide clues into individual treatment response Investigators at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute are developing a novel, multistep investigational treatment for one of the most complex and difficult-to-treat forms of the disease, locally advanced pancreatic cancer. Locally advanced pancreatic cancer has … Continue reading Unique study focuses on combined treatment approach for locally advanced pancreatic cancer

Personalized medicine may be best way to treat cancer

If a driver is travelling to New York City, I-95 might be their route of choice. But they could also take I-78, I-87 or any number of alternate routes. Most cancers begin similarly, with many possible routes to the same disease. A new study found evidence that assessing the route to cancer on a case-by-case … Continue reading Personalized medicine may be best way to treat cancer

Researchers find potential new treatment approach for pancreatic cancer

Scientists from The University of Manchester – part of Manchester Cancer Research Centre believe they have discovered a new way to make chemotherapy treatment more effective for pancreatic cancer patients. Pancreatic cancer is an aggressive cancer with poor prognosis and limited treatment options and is highly resistant to chemotherapy and radiotherapy. But researchers believe they have … Continue reading Researchers find potential new treatment approach for pancreatic cancer

Breaking down cancer’s defense mechanisms

A possible new method for treating pancreatic cancer which enables the body's immune system to attack and kill cancer cells has been developed by researchers. The method uses a drug which breaks down the protective barrier surrounding pancreatic cancer tumours, enabling cancer-attacking T cells to get through. The drug is used in combination with an … Continue reading Breaking down cancer’s defense mechanisms