Anti-androgen therapy improves survival for men with cancer recurrence after prostatectomy

Men with prostate cancer who have prostate-specific antigen recurrence following radical prostatectomy have improved survival with radiotherapy and a long-term course of anti androgen therapy. It is well established that a rising serum prostate-specific antigen (PSA) level is an indication of cancer progression in men diagnosed with prostate cancer and treated with radical prostatectomy (RP). For these … Continue reading Anti-androgen therapy improves survival for men with cancer recurrence after prostatectomy

Advertisements

Increased radiation offers no survival benefit for patients with low-risk prostate cancer

Increased radiation dose was only associated with higher survival rates in men with more aggressive cancers Increased radiation dose is associated with higher survival rates in men with medium- and high-risk prostate cancer, but not men with low-risk prostate cancer, according to a new study from Penn Medicine published this week in JAMA Oncology. Already-high survival … Continue reading Increased radiation offers no survival benefit for patients with low-risk prostate cancer

New screening method for prostate cancer recurrence

The American Cancer Society estimated that 220,800 new cases of prostate cancer will be diagnosed in the United States in 2015. Approximately 27,540 men will die of the disease, accounting for 5 percent of all cancer deaths. A common treatment for prostate cancer is a prostatectomy, in which all or part of the prostate gland … Continue reading New screening method for prostate cancer recurrence

Statin drugs can delay prostate cancer progression in patients

Men who went on cholesterol-lowering statin drugs when they began androgen deprivation therapy for prostate cancer had a longer time in which their disease was under control than did men who didn't take statins, a clinical trial led by Dana-Farber Cancer Institute investigators shows. In a study published online today by JAMA Oncology, the researchers report … Continue reading Statin drugs can delay prostate cancer progression in patients

Detecting cancer cells in blood can give an early warning of treatment failure

A blood test that measures the number of cells shed from prostate tumours into the bloodstream can act as an early warning sign that treatment is not working, a major new study shows. Researchers showed that measuring the numbers of circulating tumour cells in the blood predicted which men were benefiting least from a prostate cancer … Continue reading Detecting cancer cells in blood can give an early warning of treatment failure

HIV drug blocks bone metastases in prostate cancer

The receptor CCR5, targeted by HIV drugs, is also key in driving prostate cancer metastases, suggesting that blocking this molecule could slow prostate cancer spread. Although prostate cancer can be successfully treated in many men, when the disease metastasizes to the bone, it is eventually lethal. In a study published online in the journal Cancer Research, researchers … Continue reading HIV drug blocks bone metastases in prostate cancer

Prostate cancer in younger men — More frequent and aggressive?

Early onset prostate cancer is a newly identified, more aggressive subtype often linked to genetic mutations. The number of younger men diagnosed with prostate cancer has increased nearly 6-fold in the last 20 years, and the disease is more likely to be aggressive in these younger men, according to a new analysis from researchers at … Continue reading Prostate cancer in younger men — More frequent and aggressive?

Guidelines address long-term needs of prostate cancer survivors

New American Cancer Society Prostate Cancer Survivorship Care guidelines released today outline posttreatment clinical follow-up care for the myriad of long-term and late effects an estimated 2.8 million prostate cancer survivors in the United States may face. The guidelines are based on recommendations set forth by an American Cancer Society expert panel convened as part … Continue reading Guidelines address long-term needs of prostate cancer survivors

New model can predict therapy outcomes in prostate cancer with bone metastasis

A new computational model that simulates bone metastasis of prostate cancer has the potential to rapidly assess experimental therapy outcomes and help develop personalized medicine for patients with this disease, according to data published in Cancer Research, a journal of the American Association for Cancer Research. "Bone remodeling is a balanced and extremely well regulated process … Continue reading New model can predict therapy outcomes in prostate cancer with bone metastasis

Primary androgen deprivation therapy ineffective for most men with early prostate cancer

A study of more than 15,000 men with early stage prostate cancer finds that those who received androgen deprivation as their primary treatment instead of surgery or radiation did not live any longer than those who received no treatment. The research team, led by scientists at Georgetown Lombardi Comprehensive Cancer Center, say that the risks … Continue reading Primary androgen deprivation therapy ineffective for most men with early prostate cancer